CHROMOSOMAL ANALYSES OF CHILDREN WITH MULTIPLE CONGENITAL MALFORMATIONS.

Abstract

Ninety-five patients with multiple congenital anomalies have had chromosomal analyses performed on peripheral blood leucocytes. Seventy-five had detectable chromosome anomalies in this select group. Chromosomal analyses thus far are useful for establishing and confirming clinical diagnoses, aid in genetic counseling, and are useful tools for probing deeper into the causations of multiple congenital malformations. This sample of patients is biased by the selective population referred to Walter Reed General Hospital for consultation. However, it is obvious that chromosomal disorders are preent in the military and dependent populations at this time, and that although uncommon, they certainly are not rare. Radiation may be important in the production of chromosomal diseases. It is important to note that chromosomal abnormalities can be readily detected in the dependent populations of servicemen who have been unduely exposed to more than background radiation and diagnostic x-radiation thus far.

Document Details

Document Type
Technical Report
Publication Date
Jul 01, 1964
Accession Number
AD0606800

Entities

People

  • Robert G. Scherz

Organizations

  • Walter Reed Army Institute of Research

Tags

DTIC Thesaurus Topics

  • Abnormalities
  • Anatomy
  • Background Radiation
  • Biological Sciences
  • Blood
  • Cells (Biology)
  • Chromosomes
  • Counseling
  • Diseases And Disorders
  • Health Services
  • Hospitals
  • Leukocytes
  • Production
  • Radiation

Fields of Study

  • Medicine

Readers

  • Immunology
  • Mental Health of Military Veterans with Posttraumatic Stress Disorder (PTSD): Risk Factors, Prevalence, Symptoms, and Treatment.
  • Molecular and genetic basis of cancer.

Technology Areas

  • Biotechnology