Body Tissue Changes in Dogs Resulting from Sinusoidal Oscillation Stress
Abstract
Tissue damage resulting from varying frequency, amplitude, and duration of sinusoidal vibration is discussed. Gross post-mortem and histological observations and, in some cases, routine clinical studies of blood and urine were made. The organs found most liable to damage with vibration at 4 cps as evidenced by hemorrhage observed in histological studies were kidney, mid-brain pons, heart, lungs, and liver with less effect upon the urinary bladder, medulla, rectum, and trachea. At the higher frequencies the pituitary, stomach, duodenum, pancreas, and the midbrain also showed change. The adrenal, spleen, and sections of artery showed no histologic evidence of hemorrhage in the tests performed. Tearing occurred in soft tissues. No ligaments showed damage. Blood cell changes appeared, specifically hyperlobulation in the polynuclear neutrophils, inhomogeneities, and the appearance of intranuclear vacuoles in the nucleus of the lymphocytes. Of the 21 percent which died, most had an additional stress resulting from infection or previous renal damage. Hyperthermia appeared to be a contributing cause of the physiological changes in these tests.
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 01, 1964
- Accession Number
- AD0607758
Entities
People
- Anna Paradijeff
- John L. Nickerson
Organizations
- University of Chicago