TOXICOLOGIC EVALUATIONS OF HEXANITROETHANE
Abstract
The evaluation of the toxicity of Hexanitroethane was carried out through a series of sutudies including repeated vapor exposures to three air levels of four species of animals, short term exposures to saturated vapors, repeated application to the skin of rabbits and sensory responses of human volunteers. Evidence of toxicity as reflected by mortality and decreased weight gain was present in all species exposed repeatedly at levels of 3.0 ppm in the ambient air. Some evidence of physiological stress appeared in all species exposed to 1.0 ppm. Sensory threshold studies were conducted which indicated that eye irritation was a significant warning sign of undesirable concentrations. A suggested maximal allowable concentration in the air based on the above studies would be 0.1 ppm. In the absence of adequate ventilation to achieve this level, protective respiratory devices would be required for safe handling.
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 01, 1961
- Accession Number
- AD0608360
Entities
People
- C. H. Hine
- D. Ludlow
- Donald Decker
- G. S. Loquvam
- Gaye Eisenlord
- L. Campbell
- M. L. Dewey
- William Blucher