PYRIDOXINE (VITAMIN B6) TOXICITY LITERATURE REVIEW

Abstract

The literature from 1940 through June 1963 was surveyed to summarize the data from pyridoxine toxicity studies in animals and to ascertain the highest doses of pyridoxine (vitamin B6 analogs) that have been administered to human subjects as a therapeutic measure with no clinical evidence of toxicity. Analysis of the data indicated that doses of 25 mg/% pyridoxine hydrochloride should be well tolerated as a therapeutic measure when required. In particular, pyridoxine hydrochloride can be used when required in the specific treatment of a clinical entity such as acute UDMH intoxication.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 1964
Accession Number
AD0608841

Entities

People

  • Robert A. Schneider

Organizations

  • Air Force Research Laboratory

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Abstracts
  • Air Force
  • Air Force Facilities
  • Biomedical Research
  • Central Nervous System
  • Dimethylhydrazines
  • Diseases And Disorders
  • Glutamic Acid
  • Intoxication
  • Literature
  • Literature Surveys
  • Medical Personnel
  • Nervous System
  • Physiology
  • Seizures
  • Signs And Symptoms
  • Substance-Related Disorders

Readers

  • Theoretical Analysis.
  • Toxicology/Environmental Toxicology