POTENTIAL ANTIRADIATION DRUGS.
Abstract
N-substituted fluoroalkyl derivatives of 2-mercaptoethylamines were synthesized to serve as potential antiradiation drugs. These compounds were prepared from the thioethylation of fluoroalkylamines with ethylene sulfide. Variations in the structures of fluoroalkylamines were achieved by the development of synthetic routes towards simple fluoroalkylamines as well as fluoroalkyl-substituted aminoalcohols. A number of unsuccessful approaches towards the synthesis of 1-(and 2-)perfluoroalkyl-2-mercaptoethylamines were investigated. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 15, 1964
- Accession Number
- AD0609220
Entities
People
- John D. Behun
- Peter T. Kan