SYNAPTIC TRANSMISSION IN SYMPATHETIC GANGLIA

Abstract

Properties of the atropine-sensitive slow synaptic responses in mammalian sympathetic ganglia were further analyzed as to their 1) postsynaptic origin, 2) transmitter substances, and 3) durations of synaptic delays for each. Intracellular studies on single ganglion cells of frog's sympathetic ganglia are also reported in relation to 1) atropine-sensitivity of true after-potentials and 2) pre- and postsynaptic blocking action of curariform substances. The actions of other nicotinic blocking agents (hexamethonium, mecamylamine) on frog ganglionic synaptic responses are also reported. Developments in the technique for intracellular recording in mammalian ganglia are described.

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Document Details

Document Type
Technical Report
Publication Date
Jan 15, 1965
Accession Number
AD0609963

Entities

People

  • Benjamin Libet

Organizations

  • University of California, Berkeley

Tags

Communities of Interest

  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Amplitude
  • Atropine
  • Autonomic Nervous System
  • Brain
  • Calibration
  • Central Nervous System
  • Electrodes
  • Frequency
  • Membrane Potentials
  • Microelectrodes
  • Nerves
  • Nervous System
  • Neurotransmitters
  • Peripheral Nervous System
  • Plastic Explosives
  • Three Dimensional
  • Tissues

Fields of Study

  • Biology

Readers

  • Cardiovascular Physiology
  • Neurotoxicology