THE EFFECT OF TWO 'TRANQUILLIZERS' ON AUDITORY DISCRIMINATION AND DELAYED RESPONSE PERFORMANCE OF MONKEYS,
Abstract
Five rhesus monkeys were tested on performance of an auditory discrimination and a delayed response test with a sliding scale of increasing difficulty after treatment with (a) 0.2 to 0.5 mgm/kgm reserpine, (b) 150 mgm/kgm meprobamate, (c) an equivalent saline injection, and (d) no treatment. Both drug treatments resulted in a severe deficit on the auditory discrimination and no change or improvement in delayed response performance. The auditory deficit was not due simply to an increased latency of response. It is suggested that these results support the hypothesis that reserpine and meprobamate reduce the utilization of sensory information. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 1961
- Accession Number
- AD0611505
Entities
People
- Charles G. Gross
- Lawrence Weiskrantz
Organizations
- University of Cambridge