CHANGES IN THE PATTERNS OF IN VITRO RESPIRATION OF KITTEN DIAPHRAGMS DURING THE FIRST FEW WEEKS AFTER BIRTH,
Abstract
The pattern of respiration in vitro of hemidiaphragms from cats aged 1 to 42 days was studied. The initial rate (i.e. Q 02 in the first 30 minutes) was higher after animals had been killed traumatically than under Nembutal. The initial rate after Nembutal was indistinguishable from the steady rate (i.e. Q02 during the period 30-60 minutes) for the group killed traumatically, and both of these rates were independent of animal size. However, the initial rate (traumatic killing) and the Q02 in the presence of added succinate (whatever the method of killing) both decreased with increasing animal weight. The Q02 value in succinate was indistinguishable from that in oleate and both were higher than the initial rate. The patterns of respiration observed are discussed in terms of O2 and substrate availability and of a possible carrying over of a metabolic stimulation from in vivo to in vitro after traumatic killing. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 24, 1964
- Accession Number
- AD0612547
Entities
People
- Harold Baum
- Hosny A. El-khanagry
- Roland E. Moore
Organizations
- University of London