THE ROLE OF CEREBRAL CHOLINERGIC STRUCTURES IN LEARNING: RELATIONSHIP BETWEEN CONDITIONED RESPONSES AND THE EEG ARREST REACTION (STUDI SUL RUOLO DELLE STRUTTURE COLINERGICHE CEREBRALI NEL CONDIZIONAMENTO: RELAZIONI FRA LE RISPOSTE CONDIZIONATE E LA REAZIONE D'ARRESTO EEG),
Abstract
Earlier work by the authors had shown that atropine, in doses sufficient to alter the resting EEG and arrest reaction, also altered classical conditioned responses (i.e., affected behavior). The current report deals with other anticholinergics, a cholinesterase, and a sympathomimetic. Scopolamine and benactyzine exerted effects similar to atropine. Eserine, when administered by itself, altered both the EEG and conditioned responses; but, when administered to monkeys pretreated with an anticholinergic, it caused the EEG to return to normal and restored conditioned relfexes. Amphetamine given to monkeys pretreated with an anticholinergic did not alter the anticholinergic EEG pattern, but did restore the conditioned response. The authors propose a possible explanation for the differing effects between the cholinergic and sympathomimetic drugs. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 1963
- Accession Number
- AD0612568
Entities
People
- Gian Franco Ricci
- Luisa Zamparo
Organizations
- Sapienza University of Rome