AN IMPROVED BIOPSY TECHNIQUE FOR LIGHT AND ELECTRON MICROSCOPIC STUDIES OF HUMAN SKELETAL MUSCLE

Abstract

In order to overcome handicaps in handling muscle tissue for histological examination, a new biopsy procedure was devised and used successfully in 30 patients. Wellfixed, uniform, interpretable tissue sections were obtained for either electron microscopic or light microscopic evaluation. The biopsy procedure is primarily dependent on the use of a new surgical clamp which is in essence a modified forceps with a handle made of the usual surgical spring steel and a two-pronged fork tip of a firmer, highly corrosion-resistant stainless steel that is not chemically affected by the fixative osmium tetroxide. It has a setscrew at the midpoint of the handle which makes it possible to permanently retain the specimen and prevent it from retracting once it has been clamped and dissected free.

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Document Details

Document Type
Technical Report
Publication Date
Nov 11, 1964
Accession Number
AD0613822

Entities

People

  • David B. Sheldon
  • Edward L. Howes Jr.
  • Harold M. Price
  • Oliver D. Hutson
  • Robert T. Fitzgerald

Organizations

  • Armed Forces Institute of Pathology

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Electrons
  • Epoxy Resins
  • Filaments
  • Filter Paper
  • Fixatives
  • Health Services
  • Materials
  • Medical Personnel
  • Muscle Fibers
  • Muscles
  • New York
  • Skeletal Muscle
  • Stainless Steel
  • Steel
  • Striated Muscle
  • Tissues
  • United States

Fields of Study

  • Medicine

Readers

  • Oncology and Biomarker-Based Cancer Detection.
  • Theoretical Analysis.
  • Trauma Surgery or Emergency Medicine.

Technology Areas

  • Microelectronics