A COMPARATIVE EVALUATION OF THE ACTION OF NOVEMBICHIN, HISTAMINE, AND CHICKEN YOLK ON THE DEVELOPMENT OF EXPERIMENTAL PLAGUE,

Abstract

In single administration of novembichin and chicken yolk there was a considerable rise of the body sensitivity of albino mice to weakly virulent and avirulent Past. pestis strains; i.e., under the effect of the preparations mentioned the animals' life span was reduced more than two-fold and the possibility of isolating the Past. pestis culture increased 3-4 fold. The action of histamine in this respect was insignificant. Consequently, the administration of chicken egg yolk and novembichin may be successfully used for a more thorough investigation of the focus, detection of residual infectiousness and isolation of Past. pestis strains of low virulence. (Author)

Document Details

Document Type
Technical Report
Publication Date
Dec 01, 1963
Accession Number
AD0616769

Entities

People

  • A. V. Noramiryan
  • V. N. Zulfyan

Organizations

  • United States Army Biological Warfare Laboratories

Tags

DTIC Thesaurus Topics

  • Amines
  • Detection
  • Histamine
  • Residuals
  • Sensitivity
  • Test And Evaluation
  • Virulence

Fields of Study

  • Biology

Readers

  • Cardiovascular Physiology
  • Immunology