TOXICOLOGICAL EVALUATION OF AMMONIUM SULFAMATE-A HERBICIDE PREPARATION

Abstract

Ammonium sulfamate is a comparatively weakly toxic substance. With oral administration the LD(50) for mice equals 3.1g to 1 kg of body weight, for rats - 4.4g/kg. There were no accumulative properties of ammonium sulfamate detected. The effects of numerous exposures to an aerosol of ammonium sulfamate in concentrations of 0.25 - 0.5 g/1 caused the occurrence of desquamated catarrh of the upper respiratory tract. The application of a 20% solution of ammonium sulfamate on the skin may cause an infraction of the entirety of the surface layer of skin; there is no overall toxic influence detected during this. From a hygienic point of view ammonium sulfamate may be widely used in agriculture with the application of the usual measures of protecting the respiratory organs and exposed parts of the skin.

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Document Details

Document Type
Technical Report
Publication Date
Feb 01, 1964
Accession Number
AD0617163

Entities

People

  • M. K. Vinokurova
  • V. B. Malkova

Organizations

  • United States Army Biological Warfare Laboratories

Tags

DTIC Thesaurus Topics

  • Animals
  • Aqueous Solutions
  • Biological Laboratories
  • Blood
  • Blood Serum
  • Body Weight
  • Boiling Point
  • Herbicides
  • Industrial Hygiene
  • Inoculation
  • Laboratory Animals
  • Lethal Dosage
  • Leukocytes
  • Russian Language
  • Sulfamates
  • Sulfamic Acids
  • Translations

Readers

  • Environmental Engineering
  • Toxicology/Environmental Toxicology