SYNTHESIS OF MONOHALOCYCLOPROPANES AND 1-HALOOLEFINS VIA PHENYL-(DIHALOMETHYL) MERCURY COMPOUNDS,
Abstract
Previous studies of the synthesis of gem-dihalocyclopropanes using C6H5HgCX2Br compounds as CX2 sources were extended to an investigation of the utility of C6H5HgCHXBr compounds in the preparation of monohalocyclopropanes. It was found that both compounds (X=Cl and Br) serve excellently in the preparation of monohalocyclopropanes. A further similarity of C6H5HgCHXBr reagents to C6H5HgCX2Br compounds is seen in their reactions with triethylsilane. A new, general synthesis of vinylic bromides and chlorides based on (dihalomethyl) mercurial chemistry was developed: C6H5HgCHXBr + (C6H5)3P + RR'C=O yields RR'C=CHX + C6H5HgBr + (C6H5)3PO. This general procedure also is applicable to the preparation of olefins of type RR'C=CX2 from aldehydes and ketones. (Extracted)
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 15, 1965
- Accession Number
- AD0617596
Entities
People
- Dietmar Seyferth
- Gurdial Singh
- Harry D. Simmons Jr.
Organizations
- Massachusetts Institute of Technology