STUDIES ON POLYMER IMPLANTS IN HUMANS,
Abstract
The clinical, gross and microscopic findings in cases of plastic implanatation in humans for vascular prosthesis and for plastic surgery have been reviewed. Reactions to the following materials are included: Cellophane, Dacron, Nylon, Orlon, polyethylene, and Teflon. The plastic implants are associated with varying intensities of imflammatory reaction and fibrosis. The principal causes of functional failure are thrombosis, hemmorrhage, and excessive fibrosis. At times the hemorrhage can be shown to be due to fragmentation of the plastic with loss of mechanical integrity. No specific or characteristic inflammatory lesions were found to be due to any particular plastic. None of the tissues showed evidence of malignant changes. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 1965
- Accession Number
- AD0618243
Entities
People
- Frank B. Johnson
Organizations
- Armed Forces Institute of Pathology