THE BIOSYNTHESIS OF BIOTIN IN MICROORGANISMS. II. MECHANISM OF THE REGULATION OF BIOTIN SYNTHESIS IN ESCHERICHIA COLI,

Abstract

The mechanism of the physiological control of biotin synthesis in Escherichia coli by exogenous biotin has been studied under conditions where enzyme synthesis was inhibited by chloramphenicol or ultraviolet irradiation. The results of such studies suggest that the regulation of biotin synthesis occurs via repression rather than feedback. The experimental findings are discussed in relation to the control of vitamin and amino acid biosynthesis. (Author)

Document Details

Document Type
Technical Report
Publication Date
Jul 17, 1964
Accession Number
AD0618856

Entities

People

  • Chik H. Pai
  • Herman C. Lichstein

Organizations

  • University of Cincinnati

Tags

DTIC Thesaurus Topics

  • Amino Acids
  • Anabolism
  • Anti-Bacterial Agents
  • Bacteria
  • Escherichia
  • Escherichia Coli
  • Feedback
  • Microorganisms
  • Prokaryotes
  • Regulations

Fields of Study

  • Biology

Readers

  • Breast cancer cell signaling and growth regulation.
  • Information Retrieval
  • Microbial Pathology