SYNTHESIS OF CERTAIN PHYSIOLOGICALLY ACTIVE PHOSPHORO-ORGANIC COMPOUNDS,
Abstract
There were synthesized a series of O-ethyl-S(ethylmercaptoalkyl)-methylthiophosphinates and also Oethyl-O-(beta-ethylmercaptoethyl)-methylphosphinate and O-ethyl-O-(beta-ethylmercaptoethyl)-chloromethylphosphinate which were converted into the corresponding methylsulfomethylates. There were synthesized O-ethylO-(beta-ethylmercaptoethyl)-beta-dimethylaminoalkylphosphinates from which there were obtained the corresponding N-methylsulfomethylates. It was shown that in the action of an equimolecular quantity of dimethylsulfate on O-ethyl-(beta-ethylmercaptoethyl)-dimethylaminoalkylphosphinate there occurs alkylation with the formation of N-methylsulfomethylates, but not S-methylsulfomethylates. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 06, 1964
- Accession Number
- AD0619565
Entities
People
- E. I. Godyna
- M. I. Kabachnik
- N. N. Godovikov
Organizations
- National Air and Space Intelligence Center