HAEMOGLOBIN H DISEASE AMONG CHINESE RESIDENTS OF TAIWAN.

Abstract

Six cases of haemoglobin H disease among 5 Chinese families in Taiwan were studied. The haematological findings resembled those of previous reports and included the occurrence of the electrophoretically fast H haemoglobin component; a slight elevation in the haemoglobin F; normal amounts of haemoglobin A2; diminished red cell osmotic fragility; and the presence of red cell inclusion bodies, target cells, poikilocytosis, and reticulocytosis. The patients exhibited varying degrees of anaemia which in some cases caused little disability but which in one patient was sufficiently severe to cause death. The anaemias were microcytic and hypochromic in 4 of the 6 cases. The severity of the anaemia in the patient who died made classification difficult. The sixth case, a sister of the patient who died, had a normocytic hypochromic anaemia. (Author)

Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1965
Accession Number
AD0621183

Entities

People

  • Jeanette Tung-hsiang Huang
  • Kuo Sin Lin
  • R. Quentin Blackwell
  • Ting-chien Lee
  • Tsung-cho Lu

Tags

DTIC Thesaurus Topics

  • Anemias
  • Blood Physiological Phenomena
  • Cells
  • Cellular Structures
  • Classification
  • Diseases And Disorders
  • Elevation
  • Fragility
  • Hemoglobin
  • Inclusions

Fields of Study

  • Biology
  • Medicine

Readers

  • Immunology
  • Toxicology/Environmental Toxicology