THE USE OF GERMFREE ANIMALS IN VIRUS RESEARCH,

Abstract

Contents: Search for viruses in germfree rodents; Appearance of signs and symptoms suggestive of disease; Detection of serum antibodies against known viral agents; Detection of cytopathogenic agents in tissue cultures prepared from germfree tissues; Induction of cytopathogenic effects in germfree tissues by extracts of tissues and excretions of germfree animals; Detection of cytopathology in the tissues of germfree animals; Susceptibility of germfree rodents to standard strains of viral agents, and chemical oncogenic agents; Detection of virus in germfree mice; Application to virus research.

Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1965
Accession Number
AD0621467

Entities

People

  • M. Pollard

Organizations

  • University of Notre Dame

Tags

DTIC Thesaurus Topics

  • Antibodies
  • Biological Sciences
  • Cytopathology
  • Detection
  • Excretion
  • Signs And Symptoms
  • Standards
  • Tissue Culture

Readers

  • Immunology
  • Toxicology/Environmental Toxicology
  • Virology (or Medical Virology).