SAFE HUMAN TOLERANCE FOR HIGH CONCENTRATIONS OF CO OVER SHORT PERIODS OF TIME
Abstract
The purpose of the study was to determine concentrations of carbon monoxide in air required to give a carboxyhemoglobin increase of 7% in subjects at rest at an altitude of 10,000 feet. Exposure times of 5, 3, and 1 minute(s) and 40, 20, and 10 seconds were used. The concentrations of carbon monoxide required were 0.55, 0.975, 2.63, 3.28, 5.70, and 18.35%, respectively. When adjusted to standard conditions, these figures fit the curve derived from Pace's formula (1): Percent increase in COHb = Parts CO x MinVol x Exposure Time/42.5 x Blood Volume.
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 01, 1951
- Accession Number
- AD0622608
Entities
People
- Arthur L. Hall
- Charles A. Patterson
- James K. Colehour