HISTOPATHOLOGY OF THE DUODENAL-JEJUNAL MUCOSA OBTAINED BY CROSBY BIOPSY IN A CASE OF NUTRITIONAL MEGALOBLASTIC ANEMIA FOLIC ACID-RESPONSIVE (ISTOPATOLOGIA DELLA MUCOSA DUODENODIGIUNALE OTTENUTA CON BIOPSIA ALLA CROSBY IN UN CASO DI ANEMIA MEGALOBLASTICA NUTRIZIONALE FOLICO-RESPONSIVA),

Abstract

In a nutritional megaloblastic anemia case, responsive to folic acid, partial or subtotal atrophy of the villi was observed in the duodenal-jejunal mucosa: the epithelial cells presented, in some tracts, alterations of progressive severity, to the point of being detached, with conseguent loss of the sheathing epithelium, which was sometimes replaced by fibrinoid material on the mucosal surface. Moreover, edema and round cell infiltration of the villous tunica and of the pericryptic area, the presence of pseudocrypts, alterations of the glandular acini, and hyperplasia of the interstitial connective tissue of Brunner's glands, with a tendency to fibrosis, were also observed. (Author)

Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1964
Accession Number
AD0622748

Entities

People

  • F. Ceretto
  • G. Astaldi
  • R. Penna

Tags

DTIC Thesaurus Topics

  • Anatomy
  • Biological Pigments
  • Biological Sciences
  • Cells
  • Connective Tissue
  • Epithelial Cells
  • Epithelium
  • Fibrosis
  • Hematologic Diseases
  • Histopathology
  • Hyperplasia
  • Materials
  • Tissues

Fields of Study

  • Medicine

Readers

  • Immunology
  • Neurological Diseases/Conditions/Disorders
  • Trauma Surgery or Emergency Medicine.