UPTAKE OF CATECHOLAMINES IN THE RABBIT HEART AFTER DEPLETION WITH DECABORANE,
Abstract
After 80 - 90 per cent depletion of the rabbit heart with decaborane, injection of noradrenaline (NA) causes an increase of the amine content to near normal values. The amines taken up show normal distribution between the high speed sediment and supernatant, indicating a dynamic equilibrium between the particulate and the supernatant fractions. The amines taken up leave the heart gradually in some 20 hours. When either the 1or the d-isomer of adrenaline (A) is injected together with 1-NA. 2 - 3 times more of 1-A than of d-A is taken up for the same amount of 1-NA. The two isomers appear to leave the stores at a similar rate. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 09, 1965
- Accession Number
- AD0622770
Entities
People
- F. Lishajko
- U. S. V. Euler