THE EFFECT OF TEMPERATURE AND PH ON THE RATE OF REACTION OF CARBON MONOXIDE AND OXYGEN WITH RED BLOOD CELLS IN NORMAL AND ANEMIC SUBJECTS, AND THE EFFECT OF HYPOXIA ON PULMONARY DIFFUSION OF CO IN NORMAL AND ANEMIC SUBJECTS.

Abstract

The general objective of this work was to investigate physiologic adaptations and limitations of tissue oxygen delivery under stresses such as hypothermia, hypoxia, and/or exercise. Hypoxia was considered from the standpoints of low inspired O2 concentration and anemia. The methods of approach were: (A) Investigation of rates of gas exchange with red blood cells measured in vitro as a function of temperature and pH in normal and anemic subjects. (B) Investigation of the circulatory responses in pulmonary capillaries to alveolar hypoxia from the standpoint of gas diffusion for CO and pulmonary capillary blood flow.

Document Details

Document Type
Technical Report
Publication Date
Oct 01, 1965
Accession Number
AD0623029

Entities

People

  • W. H. Lawson Jr.

Organizations

  • State University of New York

Tags

DTIC Thesaurus Topics

  • Biological Sciences
  • Blood
  • Blood Cells
  • Blood Flow
  • Carbon Monoxide
  • Cells
  • Dielectric Gases
  • Diffusion
  • Gases
  • Hypothermia
  • Microvessels
  • Monoxides
  • Oxygen

Readers

  • Cardiovascular Physiology