THE ROLE OF NACL IN THE LYSIS OF STAPHYLOCOCCUS AUREUS BY LYSOSTAPHIN,

Abstract

Lysostaphin attacked both viable staphylococci and the mucopeptide portion of the staphylococcal cell wall. In the absence of salts, lysostaphin activity could only be recovered from the particulate portion of the lysed cell after centrifugation, whereas in the absence of salts its action on the mucopeptide resulted in a recovery of active material in both the sediment and the supernatant fluid. It appears from these observations that lysostaphin is complexed with its substrate and that NaCl is required to break the complex. (Author)

Document Details

Document Type
Technical Report
Publication Date
Apr 07, 1965
Accession Number
AD0623477

Entities

People

  • C. A. Schindler

Organizations

  • Armed Forces Institute of Pathology

Tags

DTIC Thesaurus Topics

  • Cells
  • Cellular Structures
  • Materials
  • Observation
  • Particulates
  • Recovery
  • Sediments
  • Staphylococcus Aureus
  • Substrates

Fields of Study

  • Biology

Readers

  • Microbial Pathology