THE EFFECTS OF CHEMICAL STIMULATION AND LEARNING ON NUCLEIC ACIDS AND PROTEINS.
Abstract
The effect of KC1 and of learning on the amounts of DNA, RNA, and protein/g tissue, and ratios of these three, in various brain tissue was investigated in two experiments. Four groups of rats were used in each study. One group received KC1 on both cerebral hemispheres; a second, KC1 on one hemisphere and physiological saline on the other; the third, saline on both hemispheres; and the fourther group had no chemicals injected. The results in the first experiment indicated increased activity in the dorsal cortex and lower brain stem and decreased activity in the cerebral hemispheres and upper brain stem. In Experiment 2 similar chemical treatments were involved and the animals were subjected to a learning task. The neurochemical results were not clear-cut; however, there was a suggestion that decreased activity was present in the posterior ventral cortex of rats who had KC1 on both hemispheres and whose behavior showed no evidence of learning the task of concern. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Nov 15, 1965
- Accession Number
- AD0624705
Entities
People
- James Mottin
- John Gaito
- Kenneth Koffer