RESPIRATORY DISEASES DUE TO AIR POLLUTION ON TOKYO-YOKOHAMA AREA
Abstract
The research centered upon the question of whether air pollutants, such as sulfur dioxide etc., influence the onset of asthma attack in patients as well as experimental animals. The respiratory symptoms among the patients of chronic bronchitis were followed up so as to clarify the correlation between the incidence of them and the environmental factors related to the air pollution. The results of investigation are summarized as follows: (1) The influence of sulfur dioxide to guinea pigs was studied on the experimental asthma, measuring the respiratory sensitivity to acetylcholine. Exposures to 30 ppm sulfur dioxide seemed to increase the respiratory sensitivity to acetylcholine, though statistically not significant. (2) Pulmonary diffusing capacity for carbon monoxide was measured among asthmatic patients including similar type to T-Y asthma as well as normal individuals. No significant differences were detected among D sub LCO of each group. Accordingly, it is suggested that there were no such changes among asthmatic patients including T-Y type as seen in the lung of emphysema or alveo-capillary block. (3) Patients with chronic bronchitis picked up from the previous survey were considered to be sensitive to the changes of air pollutants in the air, since the respiratory symptoms in them increased in parallel with the increase of air pollutants; i.e. dust fall, suspended particles and sulfur dioxide in the air.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 13, 1965
- Accession Number
- AD0624741
Entities
People
- Tatsushi Ishizaki
Organizations
- University of Tokyo