BIOLOGICAL PROPERTIES OF THE NIIEG TULAREMIA VACCINE STRAINS
Abstract
The NIIEG vaccine tularemia strains No. 10, 33 and 53 practically preserved all their biological characteristics in the process of a 10-year storage in a dried state (in saccharose-gelatin medium). The NIIEG vaccine strains No. 10 and 53 are harmless for guinea pigs and highly immunogenic in tests on white mice and guinea pigs, but possess an increased residual virulence for white mice in comparison with the standard Gayskiy No. 15 strain. The NIIEG vaccine strains No. 10 and 53, based both on their biological properties disclosed at the present time as well as in a test on their wide application in the past, may be recommended as reserves for the production of live tularemia vaccine. The NIIEG vaccine strain No. 33, based on agglutinability and immunogenic properties, is inferior to the other strains and cannot be recommended for the production of live vaccine.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 01, 1965
- Accession Number
- AD0625623
Entities
People
- L. V. Sirotyuk
Organizations
- United States Army Biological Warfare Laboratories