ANTIGENIC STRUCTURE OF THE BAC. ANTHRACIS VACCINAL STRAIN,
Abstract
Antigens of the vaccine strain of Bac. anthracis are localized in the capsule and cell membrane. In the composition of these structures it is possible to isolate three antigenic complexes having definite localization in the cell and possessing varied properties. The surface antigens of the capsule, the localization of which it is possible to determine in the cell with the aid of capsular fluorescent serum, are sensitive to the action of pepsin and partially trypsin and evidently are peptides. The capsular antigens proper are located in the principal layer of the capsule and are revealed both by capsular and membrane sera; they contain substances of a protein-polysaccharide nature, sensitive to the action of trypsin, chymotrypsin, hyaluronidase and lysozyme. Antigens of the cell membrane, exposed with the aid of membrane luminescent serum, contain substances sensitive to the action of lysozyme and trypsin of both a polysaccharide and protein nature. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 1964
- Accession Number
- AD0625645
Entities
People
- E. N. Levina
- L. N. Kats
Organizations
- United States Army Biological Warfare Laboratories