A STUDY OF IMMUNOGENESIS FOLLOWING VACCINATION WITH THE LIVE ASSOCIATED VACCINE. REPORT I. A STUDY OF IMMUNOGENESIS IN GUINEA PIGS VACCINATED WITH BRUCELLOSIS AND ANTHRAX VACCINE,
Abstract
During the simultaneous administration of brucellosis and anthrax vaccine, a reciprocal reaction of the organism developed in sequence: At first to anthrax, then to the brucellosis vaccine. Immunogenesis for the STI vaccine, when it is administered simultaneously with brucellosis vaccine, proceeds basically according to the type of reaction to anthrax monovaccine. During the study of immunogenesis for brucellosis vaccine when it is administered simultaneously with anthrax vaccine, facts are exposed verifying the inhibiting action of the anthrax component: (a) the vaccine culture Br. abortus 19-BA populated the organism of the quinea pig less intensively than during the administration of monovaccine; (b) the vaccine process was characterized by a weak reciprocal reaction on the part of reticuloendothelium elements. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 01, 1965
- Accession Number
- AD0625651
Entities
People
- E. A. Gubina
- M. I. Chernysheva
Organizations
- United States Army Biological Warfare Laboratories