STUDIES ON THE HEMOGLOBIN-OXYGEN EQUILIBRIUM.
Abstract
Whole blood and hemolysate from a hemoglobin M(O) heterozygote showed a lower oxygen affinity than normal adult blood and hemolysate. A decreased heme-heme interaction was also observed in the hemolysate from the patient. Extent of hybridization between human adult and canine hemoglobins decreased with the decrease of oxygen saturation of the pigments. A rough rectangular hyperbolic relation was noticed between the extent of hybridization and the degree of oxygenation. Heterogenous feature of chromaiographic fractions of rat hemoglobin was revealed on the starch-gel electrophoretic analysis of them. A simple and efficient apparatus was developed for concentrating any dilute macromolecule solution. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 17, 1964
- Accession Number
- AD0625849
Entities
People
- Itiro Tyuma