BONE MARROW AS THE MAJOR SOURCE OF POTENTIAL IMMUNOLOGICALLY COMPETENT CELLS IN THE ADULT MOUSE,

Abstract

Groups of F1 hybrid mice (A x B) were sublethally irradiated and injected with cells from various lymphoid tissues of adult parental strain (A) mice. Spleen and lymph node cells and cells from the thymus of the survivors were then injected into an F1 hybrid of another type (A x C). A significant number of deaths occurred among the secondary hosts only when they had received spleen cells from mice which had been injected with adult bone-marrow cells. (Author)

Document Details

Document Type
Technical Report
Publication Date
Dec 08, 1965
Accession Number
AD0626682

Entities

People

  • Leonard J. Cole
  • Marvin L. Tyan

Organizations

  • Naval Radiological Defense Laboratory

Tags

DTIC Thesaurus Topics

  • Anatomy
  • Biological Sciences
  • Bone Marrow
  • Bone Marrow Cells
  • Bones
  • Cells
  • Hemic And Immune Systems
  • Lymph Nodes
  • Lymphatic System

Readers

  • Immunology
  • Nuclear and Radiation Engineering.