ANTIGENIC STRUCTURE OF THE VACCINE STRAIN OF BAC, ANTHRACIS,
Abstract
Antigens of the vaccine strain of Bac. anthracis are localized in the cell capsule and membrane. Three antigen complexes, each with a definite localization in the cell and with different properties, may be distinguished in the composition of these structures. The surface antigens of the capsule, whose location could be determined in the cell by means of capsul-luminescence serum, are sensitive to the action of pepsin and partly also of trypsin and appear to be peptides. The capsule antigens proper are located in the base layer of the capsule and detected by means of both capsule and membrane sera; they contain substances of a protein-polysaccharide nature, sensitive to trypsin, chemotrypsin, hyaluronidase, and lysozyme. The antigens of the cell membrane, detected by means of membrane-luminescence sera, contain substances of both protein and polysaccharide nature, sensitive to the action of lysozyme and trypsin. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 01, 1965
- Accession Number
- AD0628492
Entities
People
- E. N. Levina
- L. N. Kats
Organizations
- United States Army Foreign Science and Technology Center