MYCOBACTERIUM ULCERANS INFECTION (WITH COMMENTS ON PATHOGENESIS)

Abstract

Mycobacterial ulceration is a severe disease affecting a large number of people living along the Nile in Uganda. In a histopathologic study of 38 cases of M. ulcerans infection, we observed one case in the preulcerative state. The lesion consisted of a central nidus of mycobacterial colonies surrounded by a wide zone of necrotic tissue. The implications of these findings have been discussed and the suggestion made that M. ulcerans elaborates a diffusible toxin that causes tissue necrosis. (Author)

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1965
Accession Number
AD0629344

Entities

People

  • Daniel H. Connor
  • H. F. Lunn

Organizations

  • Armed Forces Institute of Pathology

Tags

DTIC Thesaurus Topics

  • Animals
  • Boundaries
  • Cell Nucleus
  • Cells
  • Cellular Structures
  • Diseases And Disorders
  • Fat Cells
  • Health Services
  • Infection
  • Lymphocytes
  • Medical Personnel
  • Physicians
  • Skin
  • Subcutaneous Tissue
  • Tissues
  • United States

Fields of Study

  • Biology
  • Medicine

Readers

  • Cellular and Molecular Pathways of Apoptosis.
  • Educational Psychology
  • Infectious Disease/Epidemiology