INCAPACITATION IN THE MONKEY (MACACA MULATTA) FOLLOWING EXPOSURE TO A PULSE OF REACTOR RADIATIONS.
Abstract
One hundred and thirty-one monkeys (Macaca mulatta) were exposed to scheduled doses of 2,500 through 80,000 rads of pulsed reactor radiations using a TRIGA reactor. The animals were observed with respect to survival time, and time to permanent complete incapacitation. Additional observations of a clinical nature were made during the postirradiation course. An early transient phase of incapacitation lasting from 5 to 30 minutes was noted at dose levels from 2,500 through 30,000 rads. This was followed by a 'plateau' of recovered ability to respond, the duration of the plateau being inversely related to dose. With scheduled doses in the range from 40,000 through 80,000 rads, the plateau phenomenon was suppressed, partial recovery did not usually occur, and the early incapacitation was rapid, progressive, and irreversible. The radiological physics and dosimetry support required for this experiment is reported in detail in AD-631 589. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 01, 1966
- Accession Number
- AD0631661
Entities
People
- James T. Brennan
- Leslie J. Seigneur
Organizations
- Armed Forces Radiobiology Research Institute