HUMAN BIOCHEMICAL PARAMETERS OF ACCELERATIVE STRESS.

Abstract

Acceleration stress conditions were imposed on four healthy subjects riding the human centrifuge. Blood biochemical analyses were performed on all subjects, with the demonstration of an increase in blood glucose following centrifugation in three of the four subjects, two of whom developed 'blackout'. All four subjects developed 'greyout'. The changes in blood sugar may suggest a relationship between epinephrine secretion and graduated acceleration stress resulting in physiological changes in the subject. Changes in pooled plasma phospholipid fractions were demonstrated in blood samples obtained before and following acceleration; these changes suggest that acceleration may interfere with intracellular energy transfer mechanisms involving phosphorylated compounds associated with oxidative metabolism. The preliminary results of the pilot project indicate that further biochemical measurements may be desirable in assessing acceleration tolerance in man. (Author)

Document Details

Document Type
Technical Report
Publication Date
Apr 13, 1966
Accession Number
AD0632817

Entities

People

  • Elihu York

Organizations

  • Naval Air Warfare Center Warminster

Tags

DTIC Thesaurus Topics

  • Centrifuges
  • Chemical Compounds
  • Demonstrations
  • Energy
  • Energy Transfer
  • Epinephrine
  • Measurement
  • Membrane Lipids
  • Metabolism
  • Secretion

Readers

  • Aviation Science / Aeronautics.
  • Cardiovascular Physiology
  • Cellular and Molecular Pathways of Apoptosis.