A STUDY OF RESEARCH METHODOLOGY FOR USE IN THE DEVELOPMENT OF ANTI-RADIATION AGENTS,
Abstract
Contents: Evaluation of research procedures employed in the screening and development of effective and safe anti-radiation agents; Properties of an ideal anti-radiation agent; Present status of research methodology employed in the search for and development of anti-radiation agents; Nature and general manifestations of radiation damage and protection; Methodology and significance of the mouse screening test and of other procedures employed in the search for anti-radiation agents and in the evaluation of radiation protection potency; Survival of irradiated mice with and without a protective agent; Determination of radiation protection by measurement of intracellular recovery and of the reparative proliferation of tissues; Methods of assessment of radiation protection potency; Chemical, pharmacologic, and toxicologic properties of anti-radiation agents.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 15, 1966
- Accession Number
- AD0633394
Entities
People
- Helen M. Dyer
- Wendell H. Griffith
Organizations
- Federation of American Societies for Experimental Biology