THE ROLE OF ADRENAL CORTEX IN THE PROCESS OF ACCLIMATIZATION TO HIGH ALTITUDES.

Abstract

The results indicate that exposure to high altitude (4300 meters) causes a transitory increase in the adrenal cortex secretion of cortisol. The adrenal cortex can be further stimulated with exogenous ACTH during the first day of exposure to an environment of low oxygen tension. It is also possible to inhibit the adrenal cortex hyperactivity by dexamethasone administration. The biological half-life of a synthetic corticotrophin preparation was studied. Using a new formula for calculation results ranged between 19.4 and 38.7 minutes. (Author)

Document Details

Document Type
Technical Report
Publication Date
Apr 01, 1966
Accession Number
AD0633760

Entities

People

  • Federico Moncloa

Organizations

  • Cayetano Heredia University

Tags

DTIC Thesaurus Topics

  • Acclimatization
  • Altitude
  • Biological Phenomena
  • Biological Sciences
  • Cortisol
  • Endocrine Glands
  • Environment
  • High Altitude
  • Physiology
  • Secretion

Readers

  • Cardiovascular Physiology