BIOCHEMICAL CHANGES OCCURRING WITH ADAPTATION TO ACCELERATIVE FORCES DURING ROTATION,

Abstract

Four young men lived in a continually rotating room, 15 feet in diameter, for a period of six days. Rotational velocities on succeeding days were: 6.4, 6.4, 8.6, 10.0, 6.4, and 3.2 RPM. Stress effects measured as increased excretion rates of 17, 21 dihydroxypregnane-20-ones, eosinopenia, hyperventilation, and nausea were observed on the first day of rotation. However, adaptation was rapid, and no further stress effects were observed even with increased rotational velocity. Mild degrees of hypercalciuria, hypercapnia, and decreased norepinephrine excretion rates were observed during the last four days of the experiment as a result of the increased time spent in recumbency. (Author)

Document Details

Document Type
Technical Report
Publication Date
Apr 25, 1966
Accession Number
AD0634609

Entities

People

  • Ashton Graybiel
  • James K. Colehour

Organizations

  • Naval Aerospace Medical Institute

Tags

DTIC Thesaurus Topics

  • Diameters
  • Excretion
  • Hypercapnia
  • Memory Devices
  • Motion
  • Norepinephrine
  • Physical Properties
  • Respiration Disorders
  • Rotation
  • Signs And Symptoms
  • Symptoms And General Pathology
  • Urological Manifestations

Readers

  • Cardiovascular Physiology
  • Fluid Dynamics.
  • Mathematics or Statistics