THE ENZYMIC TRANSFORMATION OF SECONDARY NITROGEN MUSTARDS: IMPLICATIONS IN RESPIRATION

Abstract

An examination was made of the nature of the reaction between the secondary nitrogen mustart, N, N-bis(2-chloroethyl) amine (nor-HN2), and blood; and of the mechanism of the transformation of nor-HN2 in aqueous bicarbonate and blood. A previously unreported enzyme was found in human and animal blood that catalyzes carbamate formation.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 1966
Accession Number
AD0634653

Entities

People

  • Benjamin Witten
  • Charles E. Williamson
  • James G. Kirby
  • Samuel Sass

Tags

DTIC Thesaurus Topics

  • Animals
  • Aqueous Solutions
  • Arrhenius Equation
  • Blood
  • Blood Serum
  • Carbon Dioxide
  • Equations
  • Intact Stability
  • Laboratory Animals
  • Metabolic Diseases
  • New York
  • Nitrogen
  • Nitrogen Mustards
  • Partial Pressure
  • Sodium
  • Sodium Compounds
  • United States Military Academy

Readers

  • Analytical Chemistry