DEMONSTRATION OF THE PRESENCE OF BERYLLIUM IN PULMONARY GRANULOMAS

Abstract

Chronic beryllium disease was induced experimentally in dogs, and the presence of beryllium was demonstrated in specific histologic structures (pulmonary granulomas) by means of a laser microprobe and emission spectroscopy. The ability to detect minute amounts of beryllium in tissue sections of necropsy and biopsy material can be a significant aid in the diagnosis of both acute and chronic forms of beryllium disease. The detection of beryllium in histologic structures represents an important advance in the study of the pathogenesis of this disease.

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Document Details

Document Type
Technical Report
Publication Date
Sep 16, 1965
Accession Number
AD0634822

Entities

People

  • Duncan E. Mcvean
  • F. R. Robinson
  • James R. Prine
  • Solomon F. Brokeshoulder

Organizations

  • Air Force Research Laboratory

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Air Force
  • Air Force Facilities
  • Beryllium
  • Biomedical Research
  • Cells
  • Classification
  • Contracts
  • Emission
  • Emission Spectroscopy
  • Governments
  • Lymphatic System
  • Materials
  • Microprobes
  • Security
  • Spectra
  • Spectrography
  • Spectroscopy

Fields of Study

  • Medicine

Readers

  • Materials Science and Engineering.
  • Systems Analysis and Design
  • Toxicology/Environmental Toxicology

Technology Areas

  • Directed Energy