INTRODUCTION OF AROMATIC AND HETEROCYCLIC RADICALS IN FERROCENE. REACTION OF BROMO FERROCENE WITH ORGANIC MAGNESIUM COMPOUNDS.
Abstract
When an ether solution of Grignard reagent was added to a mixture of bromo ferrocene, cuprous bromide, and copper, the ether distilled, and the reaction mixture heated under nitrogen at 130 C, phenyl-alpha-thienyl- and alpha-naphthyl-ferrocenes were obtained with a yield of 75%-80%. The reaction proceded differently in the case of the allylic Grignard reagent, chlorous cyclohexylmagnesium: the reaction basically became a conversion of bromo ferrocene to ferrocene, and cyclohexene was also extracted from the reaction mixture. A mixture of alpha- and beta-pyrrole-ferrocenes was created during the interaction of bromo ferrocene with bromine pyrrole magnesium in the presence of Cu2Br2 + Cu. Idolyl bromide behaved somewhat differently in this reaction: N- and beta-indolyl-ferrocenes were produced. The structures of the compounds obtained were determined on the basis of N.M.R. Spectra.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 27, 1966
- Accession Number
- AD0636566
Entities
People
- A. N. Nesmeianov
- V. A. Sazonova
- V. N. Drozd