THE N-ALKYL ALPHA CYANOACRYLATE TISSUE ADHESIVES.
Abstract
A summary is given of studies directed toward the development of biologically receptive adhesives to be used as hemostasis inducing compounds and tissue adhesives in nonsuture closure of wounds. In addition to the usually delineated attributes of polymers for implant use, such as nontoxicity, non-allergenicity, etc., a tissue adhesive, ideally should (1) wet and spread on the tissue substrate, (2) polymerize rapidly and form a polymeric film (preferably a flexible one) which coats the tissue substrate, and (3) be biodegradable. The n-alkyl alpha cyanoacrylates fulfill these requirements to varying degrees.
Document Details
- Document Type
- Technical Report
- Publication Date
- May 01, 1966
- Accession Number
- AD0636712
Entities
People
- Fred Leonard
Organizations
- Walter Reed Army Medical Center