SKIN TUBERCULIN SENSITIVITY IN PATIENTS WITH PULMONARY TUBERCULOSIS DURING ANTIBACTERIAL THERAPY.
Abstract
CONCLUSIONS: Skin tuberculin sensitivity is definitely related to the clinical form and phase of the tubercular process. During the period of flare-up of the process, the previously given antibacterial therapy has no more effect on the nature of the tubercular sensitivity. Tuberculin sensitivity is more marked in cases of fresh infiltrative forms of pulmonary tuberculosis. Certain complications in lung tuberculosis (pleural lesions, lung hemorrhages) are accompanied by heightened sensitivity to tuberculin. Antibacterial therapy normalizes skin allergy sensitivity, increasing it in cases of hypergin reactions and lowering it in hyperegia. From the various combinations of tuberculostatic substances, the combination of streptomycin and PASA even one month after the start of therapy has a desensitizing effect in the sense of lowered sensitivity to tuberculin. Determination of tuberculin sensitivity and its dynamics in patients with pulmonary tuberculosis may serve as a test for evaluation of immunobiological changes in the conditions of antibacterial therapy. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 19, 1966
- Accession Number
- AD0638190
Entities
People
- B. M. Migdalovich
- S. P. Gefter
- T. S. Golubeva