DEFINED MAINTENANCE MEDIUM FOR SUPPORTING CHICK FIBROBLAST MONOLAYERS AND FOR PLAQUE FORMATION BY VENEZUELAN AND EASTERN EQUINE ENCEPHALITIS VIRUSES
Abstract
A defined maintenance medium that supports chick fibroblast (CF) cell monolayers in a viable state for at least 10 days and permits the formation of plaques by Venezuelan (VEE) and Eastern (EEE) equine encephalitis viruses is described. The medium consists of a balanced salts solution, glucose, 2 amino acids (L-cystine and L-histidine HC1), sodium bicarbonate, and agar. Plaque counts by VEE and EEE viruses on CF monolayers overlaid with this medium compared favorably with those obtained on a complex overlay medium.
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 23, 1964
- Accession Number
- AD0638563
Entities
People
- Eugene Zebovitz
Organizations
- United States Army Biological Warfare Laboratories