DISINFECTION WITH BPL
Abstract
Conclusions: The tests described indicate that beta-propiolactone is an excellent sterilant for the air and surfaces in closed chambers. A calculated concentration of six milligrams of BPL per liter of air is needed at the beginning of the contact period, followed one-half hour later by three milligrams of BPL per liter of air for a total contact time of one and one-half hours to complete the sterilization. A device that rapidly disseminates the BPL- water mixture should be used so that a sterilizing concentration is maintained during the entire contact time. The quantity of residual beta-propiolactone present one-half hour after commencing the water wash following sterilization is so negligible that tests capable of detecting one gamma per liter of air did not indicate the presence of beta-propiolactone. Tests indicated, moreover, that no neutralization of BPL or its breakdown products was needed.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 1964
- Accession Number
- AD0638565
Entities
People
- George J. Harris
- Manual S. Barbeito
- Robert L. Alg
Organizations
- United States Army Biological Warfare Laboratories