OBSERVATIONS ON THE MECHANISM OF THE HEMORRHAGES IN PLAGUE. REPORT I. STATE OF THE FACTORS OF BLOOD COAGULATION IN EXPERIMENTAL PLAGUE
Abstract
A speeding up of blood coagulation is observed in white mice and guinea pigs in the first days following infection with a virulent strain of the plague microbe. The blood coagulation time in white mice during the last stage of plague is increased. In the majority of guinea pigs no characteristic changes are detected in the blood coagulation time during this period. In plague infected laboratory animals during the process of development of the infection, the content of prothrombin in the circulating blood is decreased. Disruption of the factors of blood coagulation during experimental plague is not so great as to be a specific cause of hemorrhages.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 1965
- Accession Number
- AD0638580
Entities
People
- I. E. Kiseleva
Organizations
- United States Army Biological Warfare Laboratories