CONCERNING THE THERAPY OF EXPERIMENTAL BOTULINUM INTOXICATION BY MEANS OF LOW MOLECULAR POLYMER BLOOD SUBSTITUTES

Abstract

CONCLUSIONS: A statistically reliable therapeutic effect in white mice was obtained from the intravenous introduction of low molecular polymer blood substitutes of the polyvinylpyrrolidone and polyvinyl alcohol types on models of botulinum intoxication. Subcutaneous introduction of these preparations proved to be ineffective. Introduction of groups of high reactive capability (acids, amines, sulfhydryl) to the structure of low molecular polymer blood substitutes did not increase the therapeutic value of these preparations during botulinum intoxication.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 1965
Accession Number
AD0638594

Entities

People

  • L. N. Zhuk

Tags

DTIC Thesaurus Topics

  • Alcohols
  • Animals
  • Biodegradable Plastics
  • Biological Laboratories
  • Blood Substitutes
  • Chemical Compounds
  • Chemical Reactions
  • Copolymers
  • Intoxication
  • Military Medicine
  • Polymers
  • Polyvinyl Alcohol
  • Polyvinyls
  • Rodents
  • Russian Language
  • Sodium Compounds
  • Vinyl Alcohol

Fields of Study

  • Chemistry
  • Medicine

Readers

  • Immunology
  • Molecular and Cellular Biochemistry
  • Polymer Science and Engineering.