POSTIRRADIATION CREATINURIA IN MACACA MULATTA PRIMATES

Abstract

Macaca mulatta primates irradiated by Co60 gamma rays in three groups of four animals each to dose levels of 2,000, 4,000, and 6,000 rads showed marked creatinuria. Refinement of the fluorometric determination of creatine based on the reaction of ninhydrine with creatine in alkaline media has been achieved. Interfering guanido compounds calculated on a creatine equivalence constituted from unmeasurable amounts to approximately 10% of the total creatine in samples containing a small amount of creatine.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 1966
Accession Number
AD0638622

Entities

People

  • H. E. Hamilton
  • I. G. Peters

Organizations

  • United States Air Force School of Aerospace Medicine

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Abstracts
  • Acids
  • Aerospace Medicine
  • Air Force
  • Air Force Facilities
  • Animals
  • Classification
  • Contractors
  • Contracts
  • Creatine
  • Creatinine
  • Gamma Rays
  • Government Procurement
  • Governments
  • Hydrochloric Acid
  • Radiation
  • Standards

Fields of Study

  • Medicine

Readers

  • Analytical Chemistry
  • Nuclear and Radiation Engineering.
  • Toxicology/Environmental Toxicology