AN INVESTIGATION OF BIOLOGICAL SYSTEMS BY SLOW NEUTRON INELASTIC SCATTERING.
Abstract
Several systems of biological interest have been investigated by slow neutron inelastic scattering. The frequencies of molecular vibrations in a 40-800/cm range have been obtained for several polypeptides (polyglutamic acid (PGA), polyglycine, polyleucine). Under certain approximations, the frequency distribution g(mu) of phonons in the sample can be extracted from the scattered neutron intensity. This function g(mu) can in turn be used to calculate some of the thermodynamic parameters such as free energy, enthalpy, or specific heat. This has been applied to the study of the alpha-helix-random coil transition in PGA, and to the denaturation of bovine serum albumun (BSA). Preliminary results on the 'melting' of keratin structure in 7-8 LiBr solution are also presented. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 01, 1966
- Accession Number
- AD0638991
Entities
People
- H. P. Boutin
Organizations
- Picatinny Arsenal