FORMATION OF METHYLENE BRIDGES IN THE REACTION OF RIBONUCLEIC ACID WITH FORMALDEHYDE
Abstract
From RNA, processed with formaldehyde, a product of the condensation of adenosine with formaldehyde was isolated. It was identified by chromatographic mobility and UV spectrum as methylene-bis-adenosine. In the alkaline hydrolyzate of RNA, treated with C14H2O, C14-methylene-bis-adenylic acid was detected chromatographically. Thus, experimental confirmation was obtained of the earlier expressed supposition concerning the formation of methylene bridges in the reaction of RNA with formaldehyde.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 1965
- Accession Number
- AD0639794
Entities
People
- M. Ya. Feldman
Organizations
- United States Army Biological Warfare Laboratories