EFFECT OF SINGLE AND REPEATED TETRACYCLINE ADMINISTRATION ON THE PHAGOCYTIC FUNCTION OF RETICULENDOTHELIAL SYSTEMS

Abstract

It was previously established that single administration of chlortetracycline and oxytetracycline to white mice stimulates the absorptive function of the reticulo-endothelial system (RES) in several cases, depending on the dose of the preparation. Clinical use of tetracyclines is practically never restricted to single administration of the preparation; therefore it is important to know whether their stimulating effects on the RES are retained upon repeated administration. The effect of single and repeated administration of chlortetracycline, tetracycline, and oxytetracycline on the absorptive function of mouse RES were studied.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 1964
Accession Number
AD0641749

Entities

People

  • G. Ya. Kivman
  • N. A. Kalinina

Organizations

  • United States Army Biological Warfare Laboratories

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  • Biomedical

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  • Anti-Bacterial Agents
  • Biological Laboratories
  • Chemotherapy
  • Confidence Limits
  • Inhibition
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  • Maryland
  • Pharmacology
  • Russian Language
  • Standardization
  • Standards
  • Translations
  • United States

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